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Tamrat Abebe Zeleke

Full name Tamrat Abebe Zeleke
Education attended BSc in Biology, Addis Ababa University, 1999

MSc in Medical Microbiology, Addis Ababa University, School of Medicine 2005

PhD in Immunology, University of Lausanne, Switzerland, 2013
Academic Rank Assistant Professor
Working for AAU Since June 2006
Awards ——recognitions — memberships of international bodies/ journals – editorial roles/ initiatives etc Member of the National Dracunculiasis [guinea worm disease (GWD)] Elimination Certification Committee

Member of the Leishmaniasis National Task Force

Member of the Technical Working Group for Revision of Guideline for Diagnosis, Treatment and Prevention of Leishmaniasis in Ethiopian

Member of the Biological Society of Ethiopia

Member of the Ethiopian Public Health Laboratory Professional Association

Member of the American Society of Microbiology

Member of the American Association of Immunologists
Address Campus: College of Health Sciences

Building: Tikur Anbessa Specialized Hospital

Floor number: 2nd

Office room no.: 76

Mobile: +251911447227

University email ID: tamrat.abebe@aau.edu.et

Alternative email ID: tabebezeleke@gmail.com
Research interest The identification of biomarkers to tropical and other infectious diseases with special interests in understanding pathogen-host interaction and immune response in infections with and without HIV co-infection; understanding the dynamics of antigen-specific T cell responses in breast and cervical cancer; understanding the mechanisms of protection and pathogenesis responsible for cancer.
Publications in reputable journals
  1. Garedew L, Mihret A, Mamo G, Abebe T, Firdessa R, Bekele Y, Ameni G. Strain diversity of mycobacteria isolated from pulmonary tuberculosis patients at Debre Birhan Hospital, Ethiopia. Int J Tuberc Lung Dis. 2013; 17(8):1076-81. doi: 10.5588/ijtld.12.0854.
  2. Abebe T, Takele Y, Weldegebreal T, Cloke T, Closs E, Corset C, Hailu A, Hailu W, Sisay Y, Corware K, Corset M, Modolell M, Munder M, Tacchini-Cottier F, Müller I, Kropf P. Arginase activity – a marker of disease status in patients with visceral leishmaniasis in Ethiopia. PLoS Negl Trop Dis. 2013; 7(3):e2134. doi: 10.1371/journal.pntd.0002134.
  3. Takele Y, Abebe T, Weldegebreal T, Hailu A, Hailu W, Hurissa Z, Ali J, Diro E, Sisay Y, Cloke T, Modolell M, Munder M, Tacchini-Cottier F, Müller I, Kropf P. Arginase Activity in the Blood of Patients with Visceral Leishmaniasis and HIV Infection. PLoS Negl Trop Dis. 2013; 7(1):e1977. doi: 10.1371/journal.pntd.0001977.
  4. Garedew L, Mihret A, Abebe T, Ameni G. Molecular typing of mycobacteria isolated from extrapulmonary tuberculosis patients at Debre Birhan Referral Hospital, central Ethiopia. Scand J Infect Dis. 2013; 45(7):512-8. doi: 10.3109/00365548.
  5. Utaile M, Kassahun A, Abebe T, Hailu A. Susceptibility of clinical isolates of Leishmania aethiopica to Miltefosine, Paromomycin, Amphotericin B and Sodium Stibogluconate using amastigote-macrophage in vitro model. Exp Parasitol. 2013; 134(1):68-75. doi: 10.1016/j.exppara.2013.01.022.
  6. Abebe T, Hailu A, Woldeyes M, Mekonen W, Bilcha K, Cloke T, Fry L, Seich Al Basatena NK, Corware K, Modolell M, Munder M, Tacchini-Cottier F, Müller I, Kropf P. Local increase of arginase activity in lesions of patients with cutaneous leishmaniasis in Ethiopia. PLoS Negl Trop Dis. 2012; 6(6):e1684. doi: 10.1371/journal.pntd.0001684.
  7. Ali S, Abera S, Mihret A, Abebe T. Association of Hepatitis C Virus Infection with Type II Diabetes in Ethiopia: A Hospital-Based Case-Control Study. Interdiscip Perspect Infect Dis. 2012; 354656. doi: 10.1155/2012/354656
  8. Shiferaw Y, Abebe T, Mihret A. Sharps injuries and exposure to blood and bloodstained body fluids involving medical waste handlers. Waste Manag Res. 2012; 30(12):1299-305. doi: 10.1177/0734242X12459550
  9. Shiferaw Y, Abebe T, Mihret A. Hepatitis B virus infection among medical waste handlers in Addis Ababa, Ethiopia. BMC Res Notes. 2011; 4:479. doi: 10.1186/1756-0500-4-479.
  10. Gelanew T, Kuhls K, Hurissa Z, Weldegebreal T, Hailu W, Kassahun A, Abebe T, Hailu A, Schönian G. Inference of population structure of Leishmania donovani strains isolated from different Ethiopian visceral leishmaniasis endemic areas. PLoS Negl Trop Dis. 2010; 4(11):e889. doi: 10.1371/journal.pntd.0000889.
  11. Cloke TE, Abebe T, Hailu A, Munder M, Taylor GP, Müller I, Kropf P. Antiretroviral therapy abrogates association between arginase activity and HIV disease severity. Trans R Soc Trop Med Hyg. 2010; 104(11):746-8. doi: 10.1016/j.trstmh.2010.08.004.
  12. Golassa L, Abebe T, Hailu A Evaluation of crude hydatid cyst fluid antigens for the serological diagnosis of hydatidosis in cattle. J Helminthol. 2011; 85(1):100-8. doi: 10.1017/S0022149X10000349.
  13. Cloke TE, Garvey L, Choi BS, Abebe T, Hailu A, Hancock M, Kadolsky U, Bangham CR, Munder M, Müller I, Taylor GP, Kropf P. Increased level of arginase activity correlates with disease severity in HIV-seropositive patients. J Infect Dis. 2010; 202(3):374-85. doi: 10.1086/653736.
  14. Gelanew T, Amogne W, Abebe T, Kuhls K, Hailu A, Schönian G. A clinical isolate of Leishmania donovani with ITS1 sequence polymorphism as a cause of para-kalaazar dermal leishmaniasis in an Ethiopian human immunodeficiency virus-positive patient on highly active antiretroviral therapy. Br J Dermatol. 2010; 163(4):870-4. doi: 10.1111/j.1365-2133.2010.09768.x.
  15. Modolell M, Choi BS, Ryan RO, Hancock M, Titus RG, Abebe T, Hailu A, Müller I, Rogers ME, Bangham CR, Munder M, Kropf P. Local suppression of T cell responses by arginase-induced L-arginine depletion in nonhealing leishmaniasis. PLoS Negl Trop Dis. 2009; 3(7):e480. doi: 10.1371/journal.pntd.0000480.
  16. Müller I, Hailu A, Choi BS, Abebe T, Fuentes JM, Munder M, Modolell M, Kropf P. Age-related alteration of arginase activity impacts on severity of leishmaniasis. PLoS Negl Trop Dis. 2008;2(5):e235